Comfortis™ PLUS is an oral tablet top be taken with food. Comfortis Plus starts killing fleas in just 30 minutes, plus provides the added benefit of protection against intestinal worms such as hookworm, roundworm and whipworm infections. For immediate relief and month long protection, Comfortis™ PLUS is available in a convenient beef flavoured, chewable tablet.
Safe for puppies from 8 weeks of age
Comfortis™ PLUS Chewable Tablets are available in variable strengths of spinosad + milbemycin oxime for oral administration to dogs.
Milbemycin oxine interferes with nerve transmission in invertebrates, which helps protect against heartworm, roundworm, hookworm and whipworm (minimum dose rate 0.5mg/kg)
Comfortis™ PLUS can be administered to puppies from 8 weeks of age. Puppies less than 14 weeks of age may experience an increased rate of vomiting. Seek veterinary advice regarding the use of Comfortis™ PLUS in pregnant and lactating females, and in dogs with pre-existing epilepsy.
The safe use of Comfortis™ PLUS in breeding males has not been evaluated.
Concurrent use of Comfortis™ PLUS with high extra-label doses of ivermectin for parasitic mange or demodicosis may be associated with an increased risk of developing neurological signs typically associated with ivermectin toxicity. Comfortis™ PLUS should not be administered concurrently with extra-label high doses of macrocyclic lactones.
The use of Comfortis™ PLUS in dogs suffering from microfilaremia is not recommended. On rare occasions, transient shock-like (hypersensitivity) reactions have been observed in heartworm positive animals carrying a high number of microfilariae at the time of the first treatment with milbemycin oxime. Dogs with an existing adult D. immitis heartworm infection should be treated with an adulticide prior to commencement of Comfortis™ PLUS.
The following adverse events have been recorded following administration of spinosad and milbemycin oxime together: vomiting, pruritis, lethargy and diarrhoea.
Comfortis™ PLUS tablets are given orally, once a month at the recommended minimum dosage of 30 mg/kg body weight spinosad and 0.5 mg/kg milbemycin oxime as specified in the following table
Comfortis™ PLUS should be administered with food for maximum effectiveness. Comfortis™ PLUS may be consumed as a treat by dogs when offered by the owner just prior to feeding. Alternatively, Comfortis™ PLUS may be offered in food or administered like other tablet medications, in conjunction with a meal. To ensure that the entire dose is consumed, watch your dog for several minutes following tablet administration. If the entire dose is not consumed, re-dose as soon as possible with the full dose.